Month: January 2016

Who Can Take Part In Clinical Trials?

dClinical trials have become very popular in the modern world because people have realized its importance and how they can help to eradicate illness. This is the reason why millions of people take part in clinical trials today.

Some people might take part because they have no other choice. The medicines that are already available to them might not be working, so they opt to take a medicine on a trial. In the clinical trials, they are tested with new medicines, which nobody has used or seen. These medicines are different from the ones they have used in the past. Though the main ingredient might be the same, there might have been some new added ingredients that they have developed for the trial. This new medicine might be just want is needed to save a patient’s life.

People take part in the clinical trials in a hope that these trials would help them be a better person health wise. The trials are carried out by the experienced researchers who constantly find new ways to make the medicines more effective.

Many times, they have had a breakthrough in the field of medicinal science and surgical procedures, and that has helped millions of patients. The main purpose of carrying out the clinical research is to see if the advancement in the field will work. It enables us to find new ways to detect, prevent and treat a number of diseases, such as cancer, arthritis, tumors and more.

The advancement can be in the form of anything from new drugs, to surgical procedures or even using both to treat a disease. If you belong to a clinical research company and are looking to find volunteers who can participate in the clinical trials, then you should go and ask in hospitals. Just make sure that you have permission to ask patients, don’t just turn up and start asking questions because this will put people off.

A hospital is a place where you will see a lot of patients who suffer from certain diseases or conditions and they have tried everything to be cured. These clinical trials are the last hope for them and they are just hoping that you get the results that might save their lives. So, you have to be sensitive.

Things can go in the opposite direction as well, so the patients must be aware of the risk factor that is involved with the clinical trials. The biggest advantage for the patients is that they get to try the medicines, which if passed would be sold for hundreds of thousands of dollars, but they will be trying it for free. Moreover, patients suffering from HIV/AIDS and cancer are the ones who can really benefit from the medication because if the trial is successful, then the danger of the disease would go down significantly, leading to a better life expectancy rate.

Clinical trials are not for everybody. Some patients can withstand new medicines, while others get certain reactions, such as spots on the skin, headaches, anxiety or any other symptom. Therefore, you must have guidelines in place so the patients know what to expect. You will also need to know if the patient is sensitive to certain ingredients or has any allergies. You could do that by giving prospective patients a questionnaire to complete before they start the trial.

If the patients check all the desired boxes, then they can advance to the next round where they will meet the researchers to determine if they are eligible or not. Then, the patients have to go through a medical examination where they will be asked as many questions as possible to make sure that they are the right candidates. Patients can ask questions as well, just to clear up any doubts that they might have about the clinical trials. You must tell patients to consult their family before taking part in the trial.

Joint Replacement Risks to Be Aware of

eJoint replacement is a surgical option when the joint is damaged to such an extent that it hampers free movement and causes extreme pain. The decision to undergo such a surgery is difficult. There is a lot of apprehension around how it is done, what materials are used for the artificial joints, do many people undergo such a surgery and what are the after effects?

Well, to answer all these questions in short, joints that are irreversibly damaged require replacement. Replacing a damaged joint can help you move around and feel better. Damage to the joint could be due to arthritis, accidents, sports injuries and other such diseases that cause swelling and stiffness of the joints. The replaced joint is generally made up of plastic or metal or a combination of both. The new joints last nearly 10 – 15 years.

Now, looking at the risks, joint replacement surgery like any other surgery has its own risks. Here are the after effects that you need to be aware of. Remember that most of the after effects are treatable so, make sure that you contact your doctor immediately if you see the following symptoms.

Infection

The foremost risk of a joint replacement surgery is infection. This infection can occur around the wound or in the wound. The infection may be seen during your hospital stay, or a few days after you leave. Well, sometimes infections occur years after the surgery. Minor infections can be treated with drugs but if the infection is deep, a re-surgery may be required.

Blood Clots

Blood clots may be seen and lumps of blood can form in and around the wound. After a period of time, these clots cause pain and swelling in those areas. Doctors generally suggest drugs that can make your blood thin. Special stockings, exercises or boots can also help your blood move faster.

Loosening

The new joint may loosen. This causes pain and a lot of discomfort. Contact your doctor immediately as this requires a re-operation to relocate the joint.

Dislocation

Sometimes the ball of the prosthesis may come out of its socket. Many a times this can be treated without surgery. Operation may be required depending on the severity.

Wear

Some wear is bound to happen in a joint over time. If it is too serious, contact your doctor. This wear causes loosening of the joint and cause additional discomfort.

Nerve and Blood Vessel Injury

It is possible that the nerves near the replaced joint are damaged during surgery. This is not very common, but if there is a minor damage, it heals itself over time.

It’s always a good idea to inform your doctor about any of the above symptoms as early as possible.

Gift Ideas For Your Terminally Ill Loved One

lThis is something that no one likes to talk about. Terminal illness can be one of the most stressful and devastating things to watch a person go through. Perhaps it goes without saying that it is much worse for the person who is sick, and that generally necessitates that you be there for them. Most people want to offer some sort of gesture to show their concern and support, but they’re typically so overwhelmed that the most effort they’re willing to put in to buying a gift is a trip to the hospital gift shop. Understandably so. Most would naturally feel like they have more important things to be thinking about.

Of course, in spite of the fact that it seems trivial, a gift can truly be important to a sick or declining individual. We often times can become so entrenched in the more objective and medical side of things that we forget how important a patient’s feelings are to their recovery. The fact is that a person who doesn’t want to die is less likely to die than a person who does want to die; similarly, a person who believes they can get well is more likely to become healthy than a person who believes they will die.

What I’ve tried to do here is compile a list of gifts that go the extra mile to inspire your terminal loved one. Particularly things of significance across a few cultures that promote health, good luck and, most important of all to your loved on, good vibes.

Senbazuru

An ancient Japanese legend says that anybody who folds 1,000 origami cranes (referred to as senbazuru when all grouped together) will have a wish granted by a crane, typically in the form of good luck or a recovery from illness. In some versions of the legend the person making the wish must fold all 1,000 of the cranes themselves. I like to think though that the crane in question would not mind if you bought your loved one some origami paper and helped them for a little while.

Prayer Flags

You may have seen these around before in spite of their distant origins in Tibet nearly a thousand years ago. Typically a set of prayer flags consists of five square, differently colored flags. Each flag has over 400 sutras printed on it (typically via woodblock printing), each devoted to a different deity. The thought is that if the prayer flags are hung in a high up place then as they become faded and weathered their sutras permanently become a part of the universe, thereby spreading good will for everybody. It’s a great way to promote positive vibes and they are beautiful decoration as well.

Dream Catcher

This one isn’t all too unfamiliar to most in the US, especially if you live in the rockies. If you aren’t familiar with the legend, you should know that it’s a native american legend and you would do well not to further mis-appropriate this (many people hang them from their rear-view mirrors or on walls as decorative pieces). The legend goes that a woman once stopped her son from swatting a spider on the wall who was spinning her web above where the woman slept. When the boy left the spider revealed that it could talk and desired to repay the woman for her kindness. She left her web for the old woman to keep over her head when she slept, explaining that bad dreams will become entangled in it and that only her good dreams would be remembered. This gift is particularly great for anxious children and is a symbol of good luck.

By all means, if you like to keep things simple then do. We don’t all have to be Patch Adams and not all of us can be anyway. Not that folding an origami crane makes you Patch Adams, but it will likely be a welcome refrain from all the worry. Unless you’re a doctor this is the most that you can do sometimes. And that’s OK! You’re helping much more than you know by just being present. We need to de-stress and de-compress in order for our bodies to be healthy. If you can provide that opportunity to do so then you don’t need Patch Adams.

It’s a wonderful thing to be able to be there for your loved ones in times of mortal crisis. No one has ever known exactly what to say or do when their friends or family have been confronted by terminal illness. Unfortunately that means being supportive is never as easy as folding an origami crane, let alone a thousand. Just don’t forget that you deserve support too.

Treatment Options

trKidneys help filter waste and regulate other functions of your body. When kidneys fail, treatment is required to restore normal functioning of the body. There are a few choices you have for kidney treatment:

Hemodialysis – this includes a machine that filters blood outside the body.

Peritonial Dialysis – this includes the use of a lining from the belly that filters the blood inside the body.

Kidney Transplant – this includes replacing the failed kidney with a good one from a donor.

The basic function of kidneys is to remove excess fluid, minerals and waste from the blood and clean it. Kidneys are also responsible for making hormones that keep your bones strong as well as blood healthy. Kidney failure can greatly impact the normal functioning of your body. Harmful wastes may build up, blood pressure may rise considerably, the body retains excess fluid and will not be able to build enough red blood cells.

Let’s take a look at all the three treatment choices:

Hemodialysis:

A machine is used to temporarily rid your body of the harmful wastes and extra salt in the body. This in turn greatly helps control blood pressure from rising. It also helps balance other important chemicals in your body like potassium, sodium, calcium and bicarbonate.

Side effects of this treatment are infection, blockage that could be caused by blood clotting and poor blood flow. Muscle cramps and hypotension that is caused by sudden drop in blood pressure are some of the other side effects. These side effects can be avoided by proper diet and medication as directed by your doctor.

Peritonial Dialysis:

Lining from your belly or abdomen is used to filter waste from the blood. This lining is also knows as peritoneal membrane. It very aptly acts as an artificial kidney and removes excess water and salts from the body.

The most common side effect of this kidney treatment is peritonitis which is a serious abdominal infection. The opening where the catheter enters your body is infected. This can however be treated if reported immediately to the doctor.

Kidney Transplant:

Surgically replacing the damaged kidney with a healthy one is known as kidney transplant. A kidney transplant requires a doctor to test for blood type, Human Leukocyte Antigens and Cross Matching Antigens.

Transplantation of kidneys is considered closest to a cure. The new kidney needs to be a perfect match for replacement. Well, even if technically a donor kidney is a perfect match, there are chances that the body may reject your new kidney. The most common cause for this is not taking the prescribed medication. These medicines are used to stop your body’s immune system to attack the new kidney considering it as a foreign body hence causing rejection.